Cyp17a1蛋白
WebCYP17A1 ( シトクロム P450 17A1, steroid 17-alpha-monooxygenase 17α-hydroxylase/17,20 lyase/17,20 desmolase) はヒトにおいて CYP17A1 遺伝子がコードす … WebPROTAC Linker-德尔塔(Delta) - 专注化学试剂、生物试剂、分析试剂等研发用试剂知名品牌!定制生产,产品长期供货。PROTAC Linker-德尔塔(Delta) - 专注化学试剂、生物试剂、分析试剂等研发用试剂知名品牌!仅用于科研。PROTAC Linker-德尔塔(Delta) - 专注化学试剂、生物试剂、分析试剂等研发用试剂知名品牌!
Cyp17a1蛋白
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Web反馈墙 ( 0) 通用注释. 亚单元: N/A. 功能: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. http://kns55.zh.eastview.com/kcms/detail/detailall.aspx?filename=1021623197.nh&dbcode=CMFD&dbname=CMFDTEMP
WebEach serum sample from cyp17a1 +/+ XX, cyp17a1 +/+ XY, cyp17a1 –/– XX, and cyp17a1 –/– XY fish was measured in 2 dilutions and each dilution was assayed in duplicate. All necessary reagents including buffer, standard, serum samples, tracer, and antiserum, were sequentially loaded into the corresponding wells according to the ... http://yuxiqbs.cqvip.com/Qikan/Search/Index?key=A%3d%e7%a8%8b%e6%b1%89%e5%85%b4
WebJan 22, 2012 · Cytochrome P450 17A1 (also known as CYP17A1 and cytochrome P450c17) catalyses the biosynthesis of androgens in humans. As prostate cancer cells proliferate in response to androgen steroids, CYP17A1 inhibition is a new strategy to prevent androgen synthesis and treat lethal metastatic castration-resistant prostate cancer, but drug … WebApr 9, 2024 · 本研究主要探讨新疆阿魏中的化学物质、抗癌的作用机制及可能作用的靶点,通过网络药理学研究帮助筛选新疆阿魏的药效物质基础,对进一步研究其抗肿瘤作用单体成分及作用靶点提供理论基础。. 1方法. 1.1新疆阿魏有效成分及靶点的筛选. 利用草药-中医证候 ...
Web发明领域. 本发明涉及制备苯并咪唑化合物,其用作p300和/或CBP活性调节剂和因此能够用作药物物质。 发明背景
WebCYP19A1是细胞色素P450超家族(EC 1.14.14.1)的成员,它们是催化类固醇生成中许多反应的单加氧酶。. 特别地,芳香酶负责将雄激素芳构化为雌激素。. 芳香酶可以在许多组 … fobshipping poin如何用英语解释WebCYP17A1. (cytochrome P450 family 17 subfamily A member 1). 该基因编码细胞色素p450酶超家族的一个成员。. 细胞色素p450蛋白是一种单加氧酶,催化药物代谢和胆固 … fob shipping point vs fob originWebCytochrome P450 17A1 (CYP17A1; also P450c17and P450sccII) is a critically important enzyme in humans that catalyzes the formation of all endogenous androgens. It is an atypical cytochrome P450 enzyme in that it catalyzes two distinct types of substrate oxidation. Through its hydroxylase activity, it … greer guntherWeb百度百科是一部内容开放、自由的网络百科全书,旨在创造一个涵盖所有领域知识,服务所有互联网用户的中文知识性百科全书。在这里你可以参与词条编辑,分享贡献你的知识。 fob shipping point revenue recognitionWebCYP17A1蛋白屬於 細胞色素P450 氧化酶超家族的一員,定位於 內質網 ,既有甾體的17α-羥化酶也有17,20-解離酶活性,在 類固醇生成途徑 中將 孕烯醇酮 或 孕酮 的D環上17號C … greer growth and healingWebFeb 22, 2024 · 结构 [] 基因 []. CYP17A1 基因位于10号染色体的10q24.3带上包含有8个外显子 ,其cDNA全长为1527bp。. 蛋白 []. CYP17A1蛋白大小为57.4kDa ,包含有508个氨基酸残基,属于CYP450超家族 ,带有一个血红素相关活性位点以催化相关生物反应 。. CYP17A1可被两种甾类抑制剂 阿比特龙 ( 英语 : abiraterone ) 和galeterone特异 ... greer group.comWeb1.雄激素受体信号传导途径的抑制剂和p38抑制剂的药物组合,其用于治疗个体中的前列腺癌,其中前列腺肿瘤细胞表达ar-v7变体雄激素受体蛋白,或用于预防在通过雄激素受体信号传导途径的抑制剂治疗的患有前列腺癌的患者中抵抗性的发生。 2.根据权利要求1所述的用于治疗前列腺癌的药物组合 ... fob shipping point 意味