WebJun 23, 2024 · Modules corresponding to SCPN and CThPN specification, in which Fezf2 was a top-ranked gene (Fig. 5a), were specifically downregulated in knockout cells, as … Webareas. For example, CThPN establish area-specific connections with thalamic nuclei (motor cortex CThPN with VL; sensory cortex CThPN with VP; visual cortex CThPN with dLG). *these authors contributed equally to this work NIH Public Access Author Manuscript Cell. Author manuscript; available in PMC 2013 June 27. Published in final edited form as:
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WebCorticothalamic projection neurons (CThPN) are a diverse set of neurons, critical for function of the neocortex. CThPN development and diversity need to be precisely regulated, but … WebOct 9, 2013 · CThPN and SP neurons appear disorganized in Fezf2 null mice, and a number of CThPN-specific genes, including DARPP-32, Grg4, and Foxp2, fail to be expressed … flowers milltown new jersey
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Corticothalamic projection neurons (CThPN) are a diverse set of neurons, critical for function of the neocortex. CThPN development and diversity need to be precisely regulated, but little is known about molecular controls over their differentiation and functional specialization, critically limiting understanding of cortical development and complexity. WebJun 1, 2024 · CThPN development and diversity need to be precisely regulated, but little is known about molecular controls over their differentiation and functional specialization, … WebJun 24, 2016 · Identifying the genes expressed at the level of a single cell nucleus can better help us understand the human brain. Blue et al. developed a single-nuclei sequencing technique, which they applied to cells in classically defined Brodmann areas from a postmortem brain. Clustering of gene expression showed concordance with the area of … flower smiling clipart